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pentobarbital will reduce the level or result of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.pentobarbital decreases levels of vandetanib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Avoid coadministration with potent CYP3A4 inducers; these medicine lessen exposure to